World Health Organization : Technical Report Series, No. 359: World Health Organization Technical Report Series, No. 359 ; World Health Organization Expert Committee on Filariasis

By F. Hawking, Dr.

Book Id: WPLBN0000118179
Format Type: PDF eBook
File Size: 2.0 MB
Reproduction Date: 2005

Title:	World Health Organization : Technical Report Series, No. 359: World Health Organization Technical Report Series, No. 359 ; World Health Organization Expert Committee on Filariasis
Author:	F. Hawking, Dr.
Volume:
Language:	English
Subject:	Health., Public health, Wellness programs
Collections:	Medical Library Collection, World Health Collection
Historic Publication Date:
Publisher:	World Health Organization


Citation APA MLA Chicago Dr, F. H. (n.d.). World Health Organization : Technical Report Series, No. 359. Retrieved from http://www.gutenberg.cc/

Description
Medical Reference Publication

Excerpt
WHO EXPERT COMMITTEE ON FILARIASIS (WUCHERERIA AND BRUGIA JNFECTIONS) Second Report A WHO Expert Committee on Filariasis met in Geneva from 19 to 24 September 1966. Dr F. Hawking was elected Chairman, Professor M. Sasa Vice-Chairman, and Professor L. A. Jachowski, jr, Rapporteur. Opening the meeting on behalf of the Director-General, Dr A. M.-M. Payne, Assistant Director-General, said that filariasis is of great concern to many governments, particularly in developing countries, where rapid urbanization and population movements have greatly aggravated the situation. Greater and more sustained efforts will be required if any progress is to be made in its control. The present state of filariasis and of the control schemes undertaken in several countries has been assessed at a WHO Inter-regional Seminar on Filariasis held at Manila in 1965, and it has become apparent that, in spite of advances in knowledge of the epidemiology of filariasis, large-scale efforts to control the disease by mass drug treatment and by anti-mosquito measures have not everywhere yielded the expected results. Even in areas with the best results, complete interruption of transmission of the infection has not been achieved. It is recognized that, where results have not been satisfactory, this has often been due to non-technical causes such as shortage of funds and of trained staff, which have compelled the use of less expensive but also less effective control measures. Nevertheless, there is still no general agreement on the most effective and most economical ways of applying the control measures now available. Comprehensive assessments of past and present control projects are therefore needed, but require generally acceptable assessment methods to achieve comparability of results.

Table of Contents
CONTENTS Page 1 . Some recent advances in knowledge of filariasis . . . . . . . 6 1.1 The parasites . . . . . . . . . . . . . . . . . . . . . 6 1.2 Clinical manifestations . . . . . . . . . . . . . . . . . 8 2 . Methodology in epidemiological assessment . . . . . . . . . 10 2.1 Standardization of techniques and methods . . . . . . . 10 2.2 Selection of the methods to be used in surveys . . . . . 20 2.3 Presentation and analysis of parasitological survey data . . 20 3 . Chemotherapy . . . . . . . . . . . . . . . . . . . . . . . 22 3.1 Present status of diethylcarbamazine in filariasis control . 22 3.2 Present status of Me1 W . . . . . . . . . . . . . . . 25 3.3 The development of drug screening . . . . . . . . . . . 26 3.4 Testing of new conlpounds in man . . . . . . . . . . . 27 4 . Vector control . . . . . . . . . . . . . . . . . . . . . . 28 4.1 Assessment of vector control methods . . . . . . . . . 28 4.2 Review of current research and its trends . . . . . . . . 31 5. Orientation of filariasis control . . . . . . . . . . . . . . . 33 5.1 Advantages and disadvantages of chemotherapy and vector control . . . . . . . . . . . . . . . . . . . . . . . . 33 5.2 Relation of filariasis control to malaria control . . . . . 34 5.3 Clinical filariasis and the control programme . . . . . . 35 6. Terminology . . . . . . . . . . . . . . . . . . . . . . . 36 7 . Research needs . . . . . . . . . . . . . . . . . . . . . . 36 7.1 Parasitology . . . . . . . . . . . . . . . . . . . . . 36 7.2 Entomology . . . . . . . . . . . . . . . . . . . . . 37 7.3 Epidemiology . . . . . . . . . . . . . . . . . . . . . 38 7.4 Chemotherapy . . . . . . . . . . . . . . . . . . . . 38 7.5 Pathology and imn~unology . . . . . . . . . . . . . . 39 7.6 Other needs . . . . . . . . . . . . . . . . . . . . . 40 8 . Recommendations . . . . . . . . . . . . . . . . . . . . . 40 Annex . Mathematical analysis of parasitological survey data . . . 42